Megamentin – Broad-spectrum antibiotic. It has bacteriolytic (destroying bacteria) effect. Is active against a broad range of aerobic (developing only in the presence of oxygen) or anaerobic (can exist in the absence of oxygen) and gram-positive aerobic gramotriiatelnyh microorganisms, including strains that produce beta-lactamase (enzyme that destroys penicillin). Part of the preparation clavulanic acid provides resistance to the effects of amoxicillin beta-lactamase, expanding the range of its action.
Indications of Megamentin
Bacterial infections caused by sensitive microorganisms: infections of the upper respiratory tract -ostrye and chronic bronchitis (inflammation of the bronchi), equity pneumonia (inflammation of the bronchi and combined light), empyema (accumulation of pus), abscesses (ulcers) lungs; bacterial infections of skin and soft tissues; urinary tract infections – cystitis (bladder infections), urethritis (inflammation of the urethra), pyelonephritis (kidney tissue inflammation and renal pelvis); septicemia (blood poisoning microbes from home purulent inflammation) during an abortion, pelvic infection, syphilis, gonorrhea; osteomyelitis (bone marrow inflammation and adjacent bone); septicemia (blood shape microorganism infection); peritonitis (inflammation of the peritoneum); postoperative infection.
Dosing of Megamentin 375
Before assigning the patient drug to determine sensitivity to the hair, have caused disease in a particular patient. Doses set individually depending on the severity, localization of infection and susceptibility.
Children under the age of 1 year, the drug is administered as drops. Single dose for children up to 3 months. – 0.75 mL for children from 3 months. Up to a year – 1.25 ml. In severe cases, intravenous single dose for children aged 3 months. up to 12 years is 30 mg / kg body weight.
Side effects of Megamentin 375
Rarely – dyspepsia (indigestion). The severity of dyspeptic side effects may be reduced while taking the drug with food. Described isolated cases of impaired liver function, the development of hepatitis, cholestatic jaundice. There are few reports about the development of pseudomembranous colitis (intestinal colic, characterized by bouts of abdominal pain and the release of large amounts of mucus in the feces). Rarely -krapivnitsa, angioedema (allergic edema); very rarely – anaphylactic (allergic) shock poliformnaya erythema (infectious-allergic disease characterized by redness symmetric skin and temperature rise), cider Stevens-Johnson (disease characterized by redness and bleeding into mucous membranes of the mouth, urethra and conjunctiva / outer coat of the eye /), exfoliative dermatitis (redness of the whole body with its expressed ecdysis). Rarely -kandidoz (a fungal disease) and other types of superinfection (heavy, rapidly developing form of an infectious disease caused by resistant to malaria infections formerly in the body, but does not show itself). In some cases, the opportunity to develop phlebitis (vein inflammation) at the injection site.