This preparation is an agent for the treatment of various disorders male erection . Tadalafil exerts its effect by relaxing the blood vessels, which increases blood circulation in the tissues of the penis of men, resulting is a good erection. British Corporation releases drug at a tadalafil as active component called Cialis.
Effects of Tadalafil
Tadalafil is a drug that improves male erection. The drug has the ability to influence the key reactions, which constitute a single process, sexual arousal and bring the penis in an erect state. Usually, when a man is excited, the penis vessels are greatly increasing, there is a large influx of blood volume, causing the penis becomes dense, ie there comes an erection (or, in the vernacular, he “stands up”). At various erectile dysfunction there is a defect blood supply vessels of the penis. Tadalafil is a drug that increases blood circulation in the penis is, leading to a stable and good erection.
Empowered penis blood circulation is due to the expansion of blood vessels under the influence of special substances – cGMP. But cGMP enzyme is rapidly destroyed special – cGMP-specific phosphodiesterase type 5 (PDE – 5). Tadalafil inhibits (slows down) operation PDE – 5, and as a result does not decompose cGMP but acts over a longer period of time by relaxing blood vessels and helping to fill the penis with blood for the development of a normal erection. Thus, their clinical effect is Tadalafil vasodilator , or a vasodilator.
Tadalafil – instructions for use
Tadalafil tablets must be taken orally, with a small amount of water . A tablet may be taken without regard to food. The average recommended disposable drug dosage is 20 mg. A tablet with an appropriate dosage to be taken no earlier than 16 minutes before the anticipated sexual contact. After taking tadalafil can attempt of sexual intercourse for 36 hours. It is possible to set the optimum time during which develops the effect of the drug. Then the man will be able to choose the individual for himself the time for which you need to drink a pill, to hold a successful sexual intercourse. You should not abuse the frequent use of the drug.
Tadalafil is recommended to take not more than once per day. Elderly people over 65 years should take Cialis at the usual doses recommended for middle-aged men. That is, it is not necessary to adjust the dosage of the drug to men solely on the basis of advanced age. When hypersensitive 20 mg tadalafil is possible to reduce the dosage to 10 mg, 5 mg or 2.5 mg. If there is an urgent need to feel confident, then allowed to take 40 mg of drug at a time.
In this case, it should be remembered that 40 mg is the maximum daily dose of the drug. If a person takes drugs which are inhibitors of CYP3A4 enzyme such as Ketoconazole , Itraconazole , Ritonavir, Erythromycin , saquinavir, clarithromycin , telithromycin, Nefazodone and others, Tadalafil allowed to use a dose of 10 mg, and take no more than once for 72 hours ( 3 days).